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Understanding Addiction

Addiction is a dangerously misunderstood concept. It is actually the result of adaptation, and consequently the result of our bodies maintaining an equilibrium known as homeostasis.

Countless times I have encountered people who believe and pass down the many misconceptions about drug use; in particular, addiction.

The American Heritage Dictionary defines addiction as follows:

ad·dic·tion: noun

  1. Compulsive physiological and psychological need for a habit-forming
    substance: a drug used in the treatment of heroin
    addiction.
  2. The condition of being habitually or compulsively occupied with or
    or involved in something.

Before you go calling me on typos, I did notice there is a double "or" in there and it's not from my end, check my bibl. Even psychologists, the people we come to with serious issues and trust not to fry our brains like an egg on a car (this is your brain on drugs... blah blah blah), do not all properly understand addiction. It is rarely considered that addiction varies in severity, type; the personality of the so-called "addict". Thinking of addiction, there is almost always some type of withdrawal involved, be it psychological or physiological or both. But we must understand what withdrawal is; why it occurs. Our body is built on a hierarchy, and at the lowest level we find cells, an encyclopedically large array of different cells with different functions. Many people fail to realize how many different things go on in the human body in response to tiny variables. The "blowing up" of American citizens over the years has made dieting an attractive concept.

Television watchers lazily ogle the diet scam-- er- ahem- diet plan infomercials that scroll up the screen on TV Guide during the late hours of the night bearing new ways to chemically annihilate fat cells in the body in only minutes. Whilst your fat cells are dying your body is probably being severely deprived of nutrition and probably permanently damaged. Toys that come from China contain lead, and I'll bet diet pills made in China are hardly any different. Maybe if the actual workings of the situation were looked at, as opposed to having a tiny pill do it automatically, we would better make our own, much simpler and healthier decisions about our body. Whatever you eat, breathe, absorb, or in general take into your body will have some impact on your health.

You don't notice this, and some of you out there may not even believe it- why would one be unable to explicitly notice the effects of these consumed factors? The answer is homeostasis. Your body is configured to maintain an equilibrium. The food that you take in triggers other options in your body, which you usually fail to even notice because they're typically out of our realm of realization. When you eat jelly donuts, your body makes decisions to keep you healthy and limit the glucose or store it in the liver, or release more in a different situation. Such is why you crash from sugar. I may seem to be going off-topic, but I only use this as an example to aid in the simplicity of my point.

Addiction is the Result of Homeostasis

Consider this: John wakes up consumes 2 caffeine pills, after two days of dosing 2 tablets every few hours. At this point, John's body has begun adapting to caffeine's presence, and tolerance begins to occur. This is the result of the body utilizing more adenosine receptors in response to caffeine's antagonistic effect on them. This means that the body is attempting to go back to equilibrium: receptors chemically "blocked" by caffeine are replaced by new ones. The body is brilliant, but it is not self-aware. Well it kind of is, but my point is this: the body sees the changes that this chemical makes and, upon continuous reuse, the body sees the changes from the drug as permanent, in a way it is unaware of the drug, only "tricked" by it, and the body makes physical changes to maintain homeostasis.

This is a problem: changes have been made. Now, more caffeine is required to efficiently antagonize the new adenosine receptors, and tolerance continues to increase. Not only that, but if the drug is discontinued, the body is left with hyper-agonized adenosine receptors as the caffeine is suddenly gone as well as it's "numbing" effect on the receptors. Hence, withdrawal symptoms occur while the body must re-situate itself and undo the changes made to compensate for the drug's action. It's relatively similar, regardless of the drug. Drugs have effects on certain cells, and the body physically creates or destroys those cells to compensate and attempt to return to normal functionality.

Addiction is possibly one of the most dangerously misunderstood concepts our society is exposed to today. Addiction is seen as a bad thing, yet it is merely the brain responding to an unexpected change in its environment. Imagine if summer and winter were the only two seasons, and let's say winter comes only once every 15 years. Our bodies would be physically accustomed to the summer weather. Then, winter comes. People would die, not only because of cold, but suicides would occur. Seasonal depression would be rampant, the sudden lack of sun would devastate people and overall work performance would steadily decline for employed persons and unemployed persons alike. Rehabilitation clinics would not save addicts then, and rarely do they save addicts now.

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Comments (2)
#1 by jenelia, Apr 28, 2008
I totaly agree with the receptor site theory. However our body must reach equilibrium in a relatively short period of time otherwise we would be ill. Our body is not designed to function in a state out of ballance. In the presence of addcitive substances we modify our body's chemistry by overloading our circulatory system. It is a problem with overload either too many receptors or lack of receptors. With sugar crash diets it is the insulin that makes us crash after a load with simple sugars, and not the lack of sugar. Thus I totaly agree with your theory on receptors. But I totally desagree that the presence of addictive substances can keep us in an equilibroum without causing us disease.
#2 by Dezamasezon, Jun 5, 2008
I don't quite mean that the presence of addictive substances will keep us in equilibrium without causing disease, such a statement would be a generalization, and I despise generalization. Some drugs cause disease and impact health severely in a negative way when continuously administered, some do not. For example, PCP is neurotoxic, hence, it has been proven to destroy neural tissue and is a known deterrent to a healthy nervous system. Continuous use would almost unquestioningly lead to deterioration of healthy brain and nervous tissue. There are so many variables, for example, there is obviously no severe effect on the body when caffeine is consumed regularly while kept at a sensible dosage, if this were not true people worldwide would be sick and unhealthy. It is a fact, however that large amounts of caffeine over a continued time range is detrimental to a healthy mind and nervous system. Psilocybin has no known and proven negative health effects, although in one scientific study the perception changes induced by psilocybin and it's metabolites cause the mind to act in a similar way to a schizophrenic. As dosage increases, so do such tendencies to act awkwardly and inversely the ability to control oneself decreases.
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