Going down to history, there has been ranges of treatment offered for the treatment of malaria and as time goes on different scientist produce more treatment. Here is a list of solution offered with time and those who discovered them.
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340 AD: Ge Hong in China was the first person to describe the Anti-fever properties of qinghao
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Between 1620 and 1630 AD: Spanish Jesuit missionaries in Peru learn the healing power of a tree bark
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1632: Jesuit Barnabé de Cobo takes Cinchona bark to Europe
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1633: Properties of the bark in the treatment of malaria first written by Father Antanio de la Calancha
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1640: Juan de Lugo first employed the tincture of the cinchona bark for treating malaria in Countess of Chinchon
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1658: The first prescription of cinchona in England by Robert Brady
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1670s: Robert Talbor develops an infusion of cinchona powder in white wine and uses it as a "secret remedy"
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1712: Fransesco Torti writes a book on the therapeutic properties of the bark
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1742: Linnaeus, a Swedish botonist, classifies the Peruvian bark and names the tree cinchona
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1820: French chemists Joseph Pelletier and Jean Biename Caventou isolate quinine
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1844/1910: Sporadic resistance to quinine reported
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1934: Resochin (chloroquine) synthesised at Bayer, Germany by Hans Andersag
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1944: Proguanil or Paludrine (chlorguanide hydrochloride) developed by Curd, Davey and Rose
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1945, 1950: Camoquin (amodiaquin) and Primaquine (Elderfield) developed
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1952: Pyrimethamine developed
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1971: The active ingredient of qinghao isolated by Chinese scientists
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1974-75: Mefloquine jointly developed by the U.S. Army Medical Research and Development Command, World Health Organization and Hoffman-La Roche
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1992 and 1998: Atovaquone becomes available in 1992; a combination of proguanil and atovaquone, called Malarone, becomes available in Australia in 1998
