Lion Face-Like Syndrome

A man called Yang Hui Ming, suffered from this strange disease since he was four years old. At this young age, a lump as big as a mung bean grew on his left eyelid. Later this lump became bigger and bigger as time passed. When his age reached eight, this lump had already reached a diameter of 3 centimeters. Not long after that, his left forehead protruded to form a knot making his appearance resemble a lion.
Updated: The latest article: The most horrible diseases ever to tremble the world 5 (or The deadliest and most horrible diseases that shock the world).
Premature Senility

At first glance these children seem to be elderly people, perhaps in their 90s. Scientist believes that the occurrence of this disease is due to a minor error in the human genetic code. Most of the children born with these scary diseases only live up to 13 years of age. The premature death is due to the rapidly aging physical process taking place in their bodies. Forty-eight cases of this rare disease have been reported around the world.
Cushing's Syndrome

Four-year-old Xiao Xin has suffered a strange disease of "Cushing's syndrome" that causes an increase of 3 to 4kg (or 6.6 to 8.8 pounds) in her weight within half year. Sometimes, within a month, her weight can increase as much as 8kg. Up to now, this four-year-old girl has weighed as much as 70kg (or 154 pounds) while only standing 86 centimeters or approximately 34.4 inches, or less than 3 feet tall. Her weight is reported to be twice that of an obese child.
Blaschko Stripe Disease

This strange and appalling disease covers the body with these rare stripes. This disease was first found by a German Dermatology expert in 1910 while he was dissecting the human body. The stripes establish hidden pattern within human DNA. Many of the congenital and hereditary skin and mucous membranes diseases may show the appearance in accordance with this pattern and finally forms stripes on the human body.
Human Wolf Syndrome

Children who suffer from this disease will grow extremely big, with a dark appearance skin; abundant hairs grow elsewhere from parts of body, particularly near the face until the face is fully covered with variety sizes and textures of wolf-look-like fur. This disease is called human wolf syndrome. The sufferer looks like wolf.
Human Hippo syndrome

A 14-year-old Haitian girl has her face growth with a rare huge tumor weighing 7.7kg, resulting in a severe swelling deformed appearance. The timorous growth caused this child to resemble a hippo.
Elephant Leg Syndrome

This 32-year-old woman has long suffered from a syndrome called "elephant leg". Her infected left leg is 3 times as large as a normal person's leg. She often experiences pain in her left leg, and sometimes sticky mucus seeps from her leg. As a result, she often has a high fever as a complication triggered by this terrible syndrome. Over the years, she has to survive with an extremely painful life and doctors are still do not know the cause of this rare disease.
Elephant Arm Syndrome

This syndrome originates with a large black hair mole, which is generally not noticed in its early stages. During this 4-year-old boy early physical developmental stage the black hair mole began growing extensively on his left arm. The normal growth of skin and muscle has been affected.
Ichthyosis

His eyes are being burdened and crushed by both upper and lower stiffed muscles into two black empty holes. Starting from his neck, and further extending to his hands, all parts are completely covered with overlapping layers of fish-like-scales. There are many tracks of blood flowing out from the bulging areas. He has no complete fingers of ten but all his fingers tend to bend, imperfect and cramped as though forming a meat ball. How appalling when looking at them!
Severe Skin Peeling Syndrome

A 13-year-old Vietnamese boy, Nguyen, has suffered from this strange disease over the years. His skin is always in a state of cramping just like he is wearing a tight cloth. Each time when winter time arrives, his skin will peel off massively and thus causing bleeding. Because his facial skin is always experiencing intense tension and tightness, he cannot even close his eyes while sleeping.
Penis Grows on Stomach

A substance resembling a penis grows on top of his stomach creating difficulty in movement. This condition causes much frustration for the patient. This strange disease has made him going crazy for life.
Rough Leg Syndrome

A 23-year-old lady, Wan Cheng, who lives in Jiangsu in Xuzhou, has suffered great pain with this strange disease since she was 7 years old. As time passed her legs have gradually grown in size. Her left leg has grown as much as 2.1-foot in thickness.
Chan, your articles are so original. I love your work. Thanks for sharing.